Patients suffering from Fibromyalgia usually have a relatively low blood supply to some regions of the brain, particularly, thalamus area. This inadequate supply of blood levels lead to the development of one’s sensitivity towards pain and many cognitive functioning problems. This creates suitable body conditions that promote the development of Fibromyalgia with the time. Researchers have found the elevated growth of the name chemical signal, termed as substance P in the brain as one of the major causes of this condition. This chemical is the sole transmitter in the entire pain processing system of the nervous system. The abnormal growth of this substance naturally increases one’s tendencies to experience pain in various parts of the body.

In addition, it is has been proved that patients with low levels in the nerve growth factor are most susceptible to this disease. Apart from the nerve growth hormone, low levels of Somatomedin C also create habitual conditions for the aggravation of Fibromyalgia. This hormone is responsible for promoting the growth and development of the body muscles. Their inadequate presence leads to pain, feebleness of the body parts and stiffness of the bone. Further, the insufficient supply of other vital neurochemicals like, serotonin, dopamine, norepinephrine and cortisol in the brain also trigger the development of this disease.